Senior Bioinformatics Analyst

ETH Zürich • Basel • vor 2Tg

The ETH Zurich core facility NEXUS Personalized Health enables discovery and translational research for personalized health. We offer a broad range of expertise, from software engineering and biomedical data management to lab automation and screening services. Embedded in this multi-disciplinary team, the clinical bioinformatics group applies expertise in bioinformatics and statistics to the advancement of biomedical research and clinical applications.

We are recruiting a Senior Bioinformatics Analyst for the Clinical Bioinformatics Group of NEXUS Personalized Health in Basel, to commence immediately or by mutual agreement.

Job description

The primary focus of this position is the project-specific analyses of diverse high-throughput multi-omics datasets, encompassing a broad range of data types such as whole-genome and transcriptome sequencing, single-cell, and spatial data. As a Senior Bioinformatics Analyst, you will play a key role in designing, executing, and documenting analytical workflows while applying scientific rigor and best practices throughout your work.

While you will take the lead on your assigned analyses, you will work in close collaboration with the group lead and other experts within the NEXUS team. The role combines independent analytical work with active participation in joint project planning, interpretation, and dissemination of results.

Your responsibilities will also include the development and maintenance of reproducible analysis pipelines and software tools, contributing to the team's shared infrastructure. Moreover, you will help ensure that data are managed in accordance with the FAIR principles and support our partners in adopting best practices for Research Data Management (RDM).

Our projects span biomedical research and clinical diagnostics, covering a wide range of applications-from basic NGS data processing to clinical reporting and public health surveillance. NEXUS collaborates closely with academic institutions and hospitals, offering a dynamic environment where scientific excellence and collaboration drive impactful outcomes.

Profile

We are looking for a motivated and diligent colleague who enjoys working in a collaborative environment and has a strong interest in clinical science and translational research.

MSc (or higher) in bioinformatics, computational biology, or a related field
At least 3 years of hands-on experience in biomedical, genomics, or integrative research projects involving molecular datasets
Proven ability to extract biological insights and visualize complex multi-omics data
Demonstrated experience in the analysis of genomics and/or transcriptomics sequencing data
Solid programming skills in Python or R
Familiarity with HPC environments and Bash scripting
Experience with version control systems (e.g., Git)
Excellent communication skills in English

Advantageous are:

Experience with AI or machine learning methods
Background in statistics or software development
Familiarity with workflow management systems (e.g., Snakemake, Nextflow)
Knowledge of German

We offer

At NEXUS we value knowledge exchange and working together as a team, where everyone brings in their own expertise.
As a small group we have flat hierarchies, and we offer flexible working hours and family-friendly working models.
We provide training opportunities and a broad and exciting field of work, at the cutting edge of translational research.

> Working, teaching and research at ETH Zurich

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In line with our values , ETH Zurich encourages an inclusive culture. We promote equality of opportunity, value diversity and nurture a working and learning environment in which the rights and dignity of all our staff and students are respected. Visit our Equal Opportunities and Diversity website to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Sustainability is a core value for us - we are consistently working towards a climate-neutral future .